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This image comes from Anh Le, a PhD student in Laura Machesky’s lab. It is a temporal-colour image of a COS-7 cell expressing a mCherry-tagged RAB5A construct – an early endosome marker. The cells are plated on a fibronectin-coated dish and then imaged every 9 seconds for a total of 7 minutes using a super-resolution microscope system. A temporal colour code was applied to visualise the dynamic of these vesicles. Each shade of yellow represents a particular point in time for each of the vesicles. The overall back-and-forth movement of the vesicles gives an overall effect of an explosion of colours. The image won the Scottish Microscopy Society Summer 2024 imaging competition.

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Science and Art – the not so odd couple?

Posted by Sophie Morgani, on 31 July 2024

At a first, superficial glance, you could be forgiven for placing scientists and artists at the opposite ends of the career spectrum. Scientists need to be accurate and methodical. They must generate highly reproducible data while adhering to strict regulations. On the other hand, artists are often stereotyped as disorganized, free spirits, ungoverned by rules,
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Posted by 网页加速器, on 29 July 2024

Written by Shoh Asano and Ruixuan Gao Light microscopy and diffraction limit For centuries, light microscopy has played a central role in biological studies. The first implementations of a light microscope dates back to as early as the late 16th and early 17th century, when an array of polished lenses was used to magnify (biological)
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高校教师面试常见问题集_百度文库:2021-6-20 · 25.请你描述青春期男女学生的心理特点？ 【参考答案】：青少年步入青春期，心理发育迅猛，心理特点体现在： 第 1、性意识骤然增长由于生理上出现性发育加速，使得青少年对性知识特别感兴趣，对异性有强烈的交往欲望，性的好奇 感和神秘感与日俱增。

Posted by 免费加速器, on 23 July 2024

The openFrame [1] is an open-source microscopy hardware project initiated by the Photonics Group in the Physics Department at Imperial College London that is intended to provide access to a modular, upgradable, easily maintained and modifiable microscope frame that can be implemented at relatively low cost compared to existing commercial instruments. openFrame is a component
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Posted by Lucy Collinson, on 21 July 2024

Good sample preparation is, as every microscopist knows, the key to delivering sound results from an imaging experiment. In the digital age, and with the advent of big data, image analysis is also critical to extract meaningful quantitative results from image data. Indeed nowadays, the microscope itself is often the most well-developed and user-friendly part
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Take this quick X-Ray Microscopy Usage Survey!

Posted by Georgina Fletcher, on 17 July 2024

Take part in online poll to gauge use of technique and identify opportunities to expand its application The use of X-ray microscopy techniques is well established in many scientific and engineering disciplines but not all have “seen the light”. The X-ray Microscopy Focussed Interest Group (X-ray FIG) of the Royal Microscopical Society (RMS) would like
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Microscopy-related articles from our journals

  • 如何让皮肤白得发光？ - 知乎 - Zhihu:2021-4-18 · 镜像问题如何让皮肤黑得像炭？怎么护肤可众让皮肤白的发光，就是那种很健康的皮肤 我也没少买柠檬和百香果，做一罐子柠檬百香果茶放冰箱里，也榨过胡萝卜汁。 Journal of Cell Science 2024 133: jcs242834
  • Multi-sample SPIM image acquisition, processing and analysis of vascular growth in zebrafish. Development 2024 146: dev173757
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  • Object features and T4/T5 motion detectors modulate the dynamics of bar tracking by Drosophila. Journal of Experimental Biology 2024 222: jeb190017
  • SuperCLEM: an accessible correlative light and electron microscopy approach for investigation of neurons and glia in vitro. Biology Open 2024 8: bio042085

Microscopy-related preprint highlights

  • A Single-Objective Light-Sheet Microscope with 200 nm-Scale Resolution. doi: 10.1242/prelights.21204
  • Single-molecule live cell imaging of the Smc5/6 DNA repair complex. doi: 10.1242/prelights.22354

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